EFFECTS OF SEDATION WITH MODERN Α-2 AGONISTS ON PERIOPERATIVE PERIOD IN GENERAL SURGERY PATIENTS

Domoratsky A. E., Krylyuk V. O., Sozansky V. V.
Rybak K. A., Kryatchenko E. B., Beisiuk O. D.

National Medical Academy of Postgraduate Education named after P. L. Shupyk. Kyiv City Clinical Hospital ambulance

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Abstract.

α-2 agonists have a number of useful pharmacodynamic effects such as anxiolytic, sympatholytic, antinociceptive. They are very useful in the practice of anesthesia. On the other hand, their use is limited by side effects: severe hypotension and bradycardia, especially in their interaction with anesthetics. Nowadays in Ukraine are available – a long time known clonidine and deksmedetomedin — modern α-2 agonist. We learned the efficiency and safety of sedation by deksmedetomedin at a dose of 0.7 mcg / kg. Demonstrated positive effects of using deksmedetomedin in patients with acute abdominal surgical pathology.


Keywords: 
α-2 agonists, deksmedetomedin, premedication, Deksdor.

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